Studies on Wound Healing Properties of &lt;i&gt;Quercus infectoria&lt;/i&gt;

S P Umachigi,B M Vrushabendra Swamy,K N Jayaveera,G S Kumar,D V Kishore Kumar,C K Ashok Kumar

doi:10.4314/tjpr.v7i1.14677

Abstract

Purpose: The aim of the present study was to investigate the wound healing activity of the selected Indian medicinal plant Quercus infectoria. Method: Ethanol extract of the shade-dried leaves of Quercus infectoria was studied for its effect on wound healing in rats, using incision, excision and dead-space wound models, at two different dose levels of 400 and 800 mg/kg. Result: The plant showed a definite, positive effect on wound healing, with a significant increase in the levels of the antioxidant enzymes, superoxide dismutase and catalase, in the granuloma tissue. Conclusion: The efficacy of this plant in wound healing may be due to its action on antioxidant enzymes, thereby justifying the traditional claim. Keywords: Quercus infectoria, wound healing, superoxide, catalase Tropical Journal of Pharmaceutical Research Vol. 7 (1) 2008: pp. 913-919

Highlights

Quercus infectoria Olivier (Fagaceae) is a small tree found in Greece, Asia Minor andIran
In the incision wound model, a significant increase was observed in the skin tensile strength of the ethanol extract-treated group on the tenth post-wounding day, at both dose levels (Table 1)
The drug-treated animals of the dead-space wound model showed a significant increase in dry granuloma weight, granuloma breaking strength and the level of hydroxyproline content at both dose levels

Summary

Introduction

Quercus infectoria Olivier (Fagaceae) is a small tree found in Greece, Asia Minor andIran. Quercus infectoria Olivier (Fagaceae) is a small tree found in Greece, Asia Minor and. The main constituents found in the galls of Q. infectoria are tannin (50-70%) and small amounts of free gallic acid and ellagic acid. 12-14 We are unable to find any information on the woundhealing properties of this plant. The present study is an attempt to assess the efficacy of the galls using different parameters of wound healing in rats, and to study the influence of antioxidant enzymes on this property The main constituents found in the galls of Q. infectoria are tannin (50-70%) and small amounts of free gallic acid and ellagic acid. 12-14 We are unable to find any information on the woundhealing properties of this plant.

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