Abstract
Abstract Biomedical titanium alloys with Young’s moduli close to that of cortical bone, i.e., low Young’s modulus, are receiving extensive attention because of their potential in preventing stress shielding, which usually leads to bone resorption and poor bone remodeling when implants made of these alloys. They are generally β-type titanium alloys composed of non-toxic and allergy-free elements such as niobium, tantalum, zirconium etc. An alloy which belongs to this category and is highly expected to be used as a future biomaterial for implants replacing failed hard tissue is Ti-29Nb-13Ta-4.6Zr. Therefore, it is required to study anti-microbial, biological activity and corrosion resistance of this alloy which can be used as an implant material. Thus, the present study is aimed at evaluating the anti-microbial activity, biological performance and corrosion performance of Ti-29Nb-13Ta-4.6Zr (TNTZ) alloy and comparing the results by conducting similar tests on Ti-6Al-4V (Ti64) alloy and Ti-6Al-4V-2.5Cu (Ti64Cu) alloys. The hardness, Young's modulus, shear modulus and Poisson ratio of the materials were also evaluated. The anti-microbial tests conducted on the three alloys indicate that the addition of copper improved the bacterial resistance compared to other two alloys. The in vitro bioactivity of the two alloys was studied by immersing in simulated body fluid (SBF) solution. The TNTZ alloy possess better biological activity. Trace levels of apatite particles were formed on the surface of TNTZ and this was confirmed by using SEM-EDS analyses. The electrochemical corrosion studies conducted on the three materials in SBF solution indicate that the corrosion resistance of the three alloys was observed in the order of TNTZ > Ti64 > Ti64Cu. The corrosion resistance and anti-bacterial resistance were identified to be related to each other inversely.
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