Studies on the transport of glucose from disaccharides by hamster small intestine in vitro. II. Characteristics of the disaccharidase-related transport system

Abstract

The presence of disaccharidase-associated transport different from the Na +-dependent monosaccharide transport system in the hamster small intestine is confirmed. The transport of glucose from sucrose is substantially independent of Na +. In the absence of Na +, glucose released from sucrose does not mix with a pool of added free glucose but is directly transferred. Maltose, isomaltose and trehalose acf similarly to sucrose. Both moieties released from sucrose, glucose and fructose, are transferred. The extent of uptake is not related to total sucrase activity. The possibility is considered that the brush border disaccharidases may subserve a translocating “carrier” function for a part of the products of their enzymic action.