Abstract
Toxic substance, which is contained in wheat flour treated with nitrogen trichloride and causing dogs to suffer a fit like epilepsy, was separated by Bently, et al. Although it had been confirmed that this substance is a specific compound having O atom and NH group attached to S atom, its analogs have not yet been synthesized. Therefore, several of its analogs were prepared by the reaction of (2-alkylthioethyl) malonic acid with hydrazoic acid.
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