Abstract
Acid and bile are primary natural barriers in the gastrointestinal tract, and tolerances of the probiotics help to survive and exert their beneficial effects. Eight lactic acid bacteria strains were selected based on cholesterol-lowering ability from Chinese traditional kefir grain, namedlactococcus lactis subsp lactisKS4, J4, P1 and P5,lactobacillus caseiKTx, KL1 and J1 andstreptococcus thermophilusTx. The strains were cultured in MRS medium (pH 3.0 and 0.3% bile salt). Acid and bile salt tolerances were evaluated by measuring and comparing optical density values at 600nm (OD600). The o-phthalaldehyde method (OPA) was used. The cholesterol-lowering rate of strains KL1 and J1 are 60.1% and 55.3% to simulated gastrointestinal adverse circumstance in vitro. The results indicate thatlactobacillus caseiKL1 and J1 are effective as probiotics with cholesterol-lowering activities.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
