Abstract
The role of zinc in the production of atopic dermatitis (AD) was studied, and no significant differences were observed in Zn levels among patients of both AD and bronchial asthma (BA), patients with BA alone, and healthy control group.In our comparative studies, no significant differences in IgE levels were observed between patients with serum Zn≥80μg/dl and those with levels<80mμg/dl.However, most of severe cases of AD were found among patients with Zn blood level than 80μg/dl. In some cases, dermatological symptom disappeared when Zn was administrated orally. Moreover, in the comparative studies on Zn levels in hair the levels were significantly lower (p<0.01) in the AD group than in the healthy control group.These results suggest that Zn may play some role in pathogenesis of AD.
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