Studies on the Osmotic Resistance of Incubated Leptocytes.

Abstract

s1 April 1963Studies on the Osmotic Resistance of Incubated Leptocytes.A. Haut, M.D. (Associate), G. E. Cartwright, M.D. (Associate), M. M. Wintrobe, M.D., F.A.C.P.A. Haut, M.D. (Associate)Search for more papers by this author, G. E. Cartwright, M.D. (Associate)Search for more papers by this author, M. M. Wintrobe, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-58-4-732_3 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptErythrocytes from patients with thalassemia minor, iron deficiency anemia, liver disease associated with the target cells and an example of elliptocytosis were studied. These red cells are known to generally have a greater than normal osmotic resistance when studied in the fresh condition. We have found them to have an even greater osmotic resistance after their incubation in their own serum, under aseptic conditions for 24 hours, than before incubation. The increase in osmotic resistance was the opposite of the well-known change noted for normal cells under the same conditions. By virtue of this fact, the difference between the osmotic... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Salt Lake City, Utah (CS) PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byAutosomal dominant hemolytic anemia characterized by ovalocytosis 1 April 1963Volume 58, Issue 4Page: 732-733KeywordsBeta-thalassemiaCellsIron deficiency anemiaLiver diseases Issue Published: 1 April 1963 PDF downloadLoading ...