Abstract
Using a stereotaxic apparatus, electrode was implanted into the hypothalamus of the dogs before experiments and the influence of the electrical stimulation on various areas of hypothalamus on the content of PBI131 in thyroid venous blood was studied. The dogs received intramuscular injection of about 100-500 microcuries of I131 5 or 6 days before experiments. Thyroid venous blood was obtained by inserting the polyethylene catheter into the thyroid vein.When the anterior hypothalamus and the median eminence was stimulated, definite increase of PBI131 was observed, while in hypophysectomized dogs, the stimulation of these areas did not promote the thyroid hormone secretion.This would indicate that the increase of thyroid hormone secretion by the stimulation of the anterior hypothalamic area and median eminence is due to the increased secretion of thyrotropin from the pituitary gland.
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