Abstract
Hyperlipidemia is a predominant risk factor for atherosclerosis and associated cardiovascular diseases (CVD). The international guidelines issued by the World Health Organization recommend a reduction in dietary saturated fat and cholesterol intake as a means to prevent hypercholesterolemia and CVD. The main objective of the current investigation was to evaluate the effects of feeding blended oils consisting of coconut oil (CNO) with different proportions of Tiger nut oil (TNO) on serum lipid levels in Albino rats. GLC analysis was performed to illustrate the fatty acid composition of the blended oils. Blended oils were obtained by mixing tiger nut oil with coconut oil at the volume ratios of 100:0, 70:30, 50:50, 25:75, 10:90 and 0:100. Fifty-six male albino rats were randomly divided into 7 groups of 8 rats each according to the oil type. The blended oils were fed to rats for a period of up to 10 weeks. Total cholesterol (T-Ch), high-density lipoprotein cholesterol (HDL-Ch), low-density lipoprotein cholesterol (LDL-Ch), and triglycerides (TG), were determined. The atherogenic Index (AI) was calculated. The results showed that non-significant changes in all nutritional parameters were observed between the control group and the rats fed with the tested oils. The results also indicate that coconut oil had 86% saturated fatty acids. On TNO contains 66% oleic acid. Therefore, blending coconut oil with tiger nut oil can reduce the proportions of saturated to unsaturated fatty acids in CNO. The rats that were fed blended oils showed significantly reduced levels of serum cholesterol as compared to those fed CNO. The HDL levels were marginally enhanced in the rats that were fed blended oils. The total cholesterol and LDL cholesterol levels were controlled when TNO/CNO proportions varied between 25/75 and 70/30. This was reflected in the calculation of the atherogenic index. Similar changes were observed with serum triglyceride levels.
Highlights
Hypercholesterolemia and its associated cardiovascular diseases (CVD) represent one of the greatest worldwide economic, social andA.M
Dietary fat selection is known to exert a major influence on circulating cholesterol levels; they are raised with the consumption of fats containing saturated fatty acids (SFA), and reduced with fats rich in monounsaturated (MUFA) and polyunsaturated (PUFA) fatty acids (Mensink, and Katan, 1992)
Coconut oil was characterized by the presence of high levels of lower chain fatty acids C8:0, C10:0 and C12:0
Summary
Hypercholesterolemia and its associated cardiovascular diseases (CVD) represent one of the greatest worldwide economic, social andA.M. Hypercholesterolemia and its associated cardiovascular diseases (CVD) represent one of the greatest worldwide economic, social and. The relationship between plasma lipid and lipoprotein concentrations and the risk of developing cardiovascular disease (CVD) on the basis of dietary fat type is well documented (Krauss et al, 2000). Excessive cholesterol builds up in the blood, leading to plaque formation and hardening of the arteries. This condition is known as atherosclerosis, which is the leading cause of heart disease, stroke, and heart attacks (U.S Food and Drug Administration, 2004)
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
