Abstract

Gastrone, enterogastrone, and secretin have been known as the substances contained in mammalian digestive tract and having inhibitory action on the secretion of gastric juice.A glycoprotein fraction, designated as E fraction, has been isolated from the gastric mucosal layer of finback whale and found to have a marked inhibitory action on the gastric juice secretion by the authors.In order to clarify the mechanism of the inhibitory action on the gastric juice secretion, the distribution of the substance in the mucosal layer of gastrointestinal tissues from the 3rd stomach to small intestine of sperm whale was studied in this paper.

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