Abstract
Abstract Plasma of mice injected with testosterone contained a detectable increase of an erythropoietic stimulating factor (ESF). ESF was no longer present if bilateral nephrectomy was performed 8 hours prior to collecting the plasma. On the other hand if both ureters were ligated 8 hours prior to sampling, the plasma levels were even higher than in unoperated mice. The plasma ESF activity following testosterone was neutralized by incubation with antierythopoietin, suggesting its identity with erythropoietin. We propose that testosterone stimulates erythropoiesis by altering the kidneys and thereby somehow increasing erythropoietin production.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
