Studies on the Effects of Autonomic Nervous System Upon Deglutition by Cineradiographic and Digital Analyzing Method

Abstract

Cineradiographic recording and its digital analyzing method were usefull to do detailed analysis of deglutition. In this study were done the cineradiographic examinations on normal and pathologic subjects and dogs under following conditions, adrenaline, ryegostione, pilocarpine or atropine injection. For the hypothalamic experiments were used normal adult cats and dogs, which were operated under anesthesia with Nembutal. A stimulus electrode was inserted into the hypothalamus to stimulate directly. Under the rectangular electrostimulation (3-7 volts, 0.1-2m sec. 7-200 c. p. s.) was done the cineradiographic recording. Cineradiograph was analysed with digital analyser and was recorded with digital printer. According to the experiments, results were as follows. The second stage of deglutition was not altered with these drugs. Cardiac resistance and lower esophagial motility of normal subjects were reduced with atropine but were strongly raised with pilocarpine. Adrenaline and ryegostine altered them only slighly. In the pathologic subjects it was quite different, that is, lower esophageal motility was strongly reduced with atropine but not so raised with pilocarpine (Sceleroderma and Myasthenia gravis) and was slighty increased with ryegostine (Wallenbergs syndrome). Cardiac sphincter was opened and lower esophageal motility was incresed with rectangular electrostimulus of the ventromedial hypothalamic nucleus. Cardiac sphincter was closed and lower esophageal motility was suppresed with rectangular electrostimulus of lateral hypothalamic nucleus.