Abstract

The effects of the ethanol extract of Tilia cordata. Miller (Tiliaceae) were studied in vitro. using intestinal smooth muscle cells of guinea pigs dispersed by collagenase. The extract induced a dose-dependent contraction of the dispersed smooth muscle cells. The obtained data indicated a direct effect of the T. cordata. extract on the intestinal smooth muscle cells. In addition, the contractions induced by the extract were inhibited by atropine. These observations indicate involvement of some active constituents, with cholinergic properties, found in the alcohol extract to induce contraction of the intestinal smooth muscle cells via activation of the muscarinic receptors.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.