Abstract

The experiment was performed on b-classed rabbits. (1) If yakriton is subcutaneously used in the relatively large amount of 4 R. A. U. per kilo of body weight, 45 minutes prior to the injection of an 8.5% calcium gluconate solution, the curve of rise and fallis remarkably less steep and the summit less high than when the hormone is used in the amount of 2 R. A. U. (Cf. Table III in the 54th Report). (2) If a relatively large amount of calcium is used, namely 8.5% calcium gluconate solution in the amount of 5 c.c. per kilo of body weight, and injected intraperitoneally, the blood calcium content will rise rapidly, reaching a maximum in 15 minutes or 30 minutes and come down rapidly again in one and a half hours or 2 hours to almost normal figures. If yakriton is subcutaneously used in the amount of 2 R. A. U. per kilo of body weight, 75 minutes prior to the calcium injection, the blood calcium will rise more gradually and come down more gradually again, making the curve of blood calcium less steep and making the summit less high. (3) In this action the effect of yakriton to keep blood ingredients constant and normal will be seen.

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