Studies on the constituents of the root of Polygala tenuifolia Willdenow. I. Isolation of saponins and the structures of onjisaponins G and F.

Abstract

Seven triterpenoidal saponins, onjisaponins A, B, C, D, E, F, and G, were isolated from the roots of Polygala tenuifolia WILLDENOW. Among these saponins, the structures of onjisaponins G (1) and F (2) were determined on the basis of spectral and chemical evidence as presenegenin-(3)-β-D-glucopyranosido-(28)-2-O-{[β-D-apio-D-furanosyl (1→3)]-[β-D-xylopyranosyl (1→4)]-α-L-rhamnopyranosyl}-4-O-(3', 4', 5'-trimethoxycinnamoyl)-β-D-fucopyranoside and presenegenin-(3)-β-D-glucopyranosido-(28)-2-O-{[β-D-apio-D-furanosyl-(1→3)] [α-L-arabinopyranosyl (1→3)-β-D-xylopyranosyl (1→4)]-α-L-rhamnopyranosyl}-4-O-(3', 4', 5'-trimethoxycinnamoyl)-β-D-fucopyranoside, respectively.