Abstract

V79 metabolic cooperation (MC) assay was performed to detect the tumor-promoting activities of polyetherurethane (PEU), silicone and the additives of antioxidants. The inhibitory activities on the MC were first detected in both extracts prepared from PEU and silicone. PEU inhibited stronger than silicone, and furthermore the monomer of the soft segment of PEU showed the highest inhibitory activities among the constituents. As for the additives, three chemicals among eight antioxidants showed stronger inhibitory activities than BHT, a tumor promoter. Therefore, we propose that there is a possibility of tumor-promotion caused by these chemicals as well as soft segment rich oligomers extractable from the PEU.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.