Abstract
Studies on the carcinogenic action of motor engine oil additives.
Highlights
A commercial oil additive preparation has been examined for carcinogen-ic activity following skin painting in mice
caused inflammatory changes which often led to ulceration
Oil additive.-The oil additive chosen for the present study was obtained
Summary
Oil additive.-The oil additive chosen for the present study was obtained commercially in sealed cans. The additive, which consists of a soluble formulation in a mineral oil carrier, was transferred to glass-stoppered bottles and stored at room temperature. On standing for several weeks, a white sediment, as yet unidentified, was observed. No attempt was made to separate the insoluble material from the clear oil. Mice.-Stock albino mice (40) divided with respect to sex and 6-8 weeks old at the beginning of the experiment. The mice were obtained comnmercially and maintained on a cubed diet (M.R.C. diet 41) supplemented with fresh greenstuffs plus water ad libitum
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