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Abstract
The blocking antibody response has been studied in thirty-four cases of ragweed pollinosis treated with ragweed antigen. The results seem to warrant the following conclusions: 1. 1. Ragweed antigen injections definitely produce specific blocking antibody titer in ragweed-sensitive patients. 2. 2. Although high blocking antibody titers are to be found most frequently in patients who have received high total dosages of ragweed antigen, in the present study, 53 per cent of those who received high dosages did not develop high titers of blocking antibody. 3. 3. Fifty per cent of the patients treated with ragweed antigen during previous years developed high blocking antibody titers. 4. 4. Clinical results apparently do not depend upon high blocking antibody titers. The percentage of good results was identical in the patients who had low titers and in those who had high titers.
Published Version
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