Abstract

In the course of our investigations on the role of vitamins in the action of estrogens on the chick oviduct it was observed that the responses of the synthetic estrogen methoxy bisdehydro doisynolic acid (MDDA) were unique since the intragroup variation in White Leghorn chicks was extraordinarily great. This communication presents the comparative oviduct responses to MDDA, estrone, estradiol benzoate, estradiol and stilbestrol in the White Leghorn chick and the oviduct responses to MDDA and stilbestrol on the Sex-linked chicks. It is the purpose of this paper to show that the skewed response of the oviduct occurs only for MDDA. animals, methods, material The White Leghorn and Sex-linked pullets were obtained from Kerr Chickeries in Frenchtown, New Jersey. Treatment was begun on the fourth day of life and continued through the eighth day of life. The estrogens were dissolved in corn oil so that the total dose was contained in 0.5 c.c. of oil.

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