Abstract
The antimicrobial action of trimethyl-, triethyl-, tripropyl- and tributyltin chloride on bacteria, yeasts and fungi was investigated. Trialkyltin chlorides were found to have high antimicrobial action on most microorganisms, especially on fungi. The activity of these compounds on all microorganisms, except on gram-negative bacteria, increased logarithmically with an increase in the carbon number of the alkyl chains of trialkyltin chlorides. Most microorganisms treated with trialkyltin chloride lost the ability to form colonies. The activity was influenced remarkably by pH, but not by the growth phase of the microorganism. Ethylenediamine tetraacetic acid had a synergistic effect on the antimicrobial action of trialkyltin chlorides on E. coli.
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