Abstract

Summary and Conclusions Judged by plaque counts, the neutralization of 'phage by antiphagic serum was found to follow quite closely the curve of the velocity of an adsorption reaction. No evidence was obtained to indicate that the reaction follows a logarithmic curve. Results were obtained which indicate that in the neutralization of 'phage by antiphagic serum the reaction under set conditions takes place in definite proportions, provided the reaction is allowed to go to completion. The Danysz-Bordet effect was elicited, when 'phage was added in small increments to serum and, similarly, when serum was added to 'phage in small increments. Neutral serum-'phage mixtures could not be dissociated by dilution with physiological saline.

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