Abstract
Isocorydine (V) was newly isolated as an alkaloid of the fruit of Nandina domestica THUNB. Demethylation of O-methyldomesticine (I), the major alkaloid of this plant, was carried out and it was found that dl-domesticine is obtained when 36% hydrobromic acid is used and d-domesticine (II) when pyridine hydrochloride and sodium thioethoxide are used for this reaction.
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