Abstract
Quinoline 1-oxide (Ia) reacted with potassium cyanate and tosyl chloride in ethanol at -10°to give ethyl N-(2-quinolyl) carbamate (IIa) in 70% yield. The reaction under reflux caused decrease of the yield of Ia (11%) and additional formation of 2-ethoxyquinoline (IIIa) (54%) and carbostyril (IV) (29%). Unless ethanol was used, no definite product was isolated. Reactions of some derivatives of Ia as well as that of isoquinoline 2-oxide were also examined under the same conditions.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
