Abstract
Purpose: Larval hind gut of multivoltine breed silk worm Bombyx mori L. (Nistari) was studied in both favourable and unfavourable rearing seasons after Grasserie caused by Bombyx mori Nuclearpolyherosis Virus (BmNPV) using Histological Analysis, Scanning Electron Microscopy and Transmission Electronic Microscopy.
 Methodology: Chemical treatments using various bio active chemicals: Curcumin, Allicin and Azadirachtin were administered to minimize the extent of damage.
 Findings: The present study clearly indicates that Azadirachtin is more effective in comparison to its other counterparts and it is the major finding of this extensive study.
 Unique Contribution to Theory, Policy and Practice: The uniqueness of this type of bio chemical control of Grasserie disease which is not only a cost effective and eco-friendly technique, but also it is less hazardous and simple controlling procedure of Grasserie. Therefore, this extensive study may help the stakeholders to step ahead on the progression of sustainable agriculture while avoiding crop loss by means of cost-effective pathogen management technology.
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