Abstract
1. 1. Using everted sacs of sheep ileum, selenate uptake was shown to be more rapid than selenite uptake. 2. 2. Sulphate, thiosulphate and ouabain all inhibited the uptake of selenate. A Na + K +-ATPase is probably responsible for energizing the ileal brush-border transport of selenate. 3. 3. The isolated, vascularly perfused ileum was shown to absorb selenate more rapidly than selenite. 4. 4. The perfusion system described would appear to be a useful tool for studying the kinetics of intestinal absorption and the measurement of metabolic transformations within the mucosa.
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