Abstract
Summary and Conclusions The antigenicity of the so-called scarlet fever anatoxin which was produced by detoxifying scarlet fever toxin with formol and heat is due to the presence of toxoid. Rabbits can be used for the determination of antigenicity of scarlet fever anatoxin. The antigenicity of the purified and concentrated scarlet fever anatoxin described has been demonstrated by animal and human test. The antigenicity of the anatoxin prepared from scarlet fever toxin which was produced in a semi-synthetic medium has been demonstrated. The addition of alum seems to increase the antigenicity of scarlet fever anatoxin. The degree of immunity conferred on rabbits by immunization with conbined scarlet fever and diphtheria anatoxin is as high as that conveyed by a single anatoxin.
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