Studies on quinones and related compounds in higher plants. V. Model experiments for the preparation of tritium-labeled precursors for the biosynthetic studies of prenylnaphthoquinone congeners.

Abstract

Methods for the preparation of [3'-2H]-4-(2'-carboxyphenyl)-4-oxobutanoic acid and [4, 8-2H2]-2-carboxy-4-hydroxy-α-tetralone (CHT) starting from 3-methoxyphthalic anhydride have been demonstrated as model experiments for the preparation of several 3H-labeled compounds necessary for the elucidation of the biosynthetic pathways of prenylnaphthoquinone congeners occurring in Catalpa ovata.