Abstract
Acetic anhydride reacted with isoquinoline (IV) itself under reflux to give an addition product, whereas quinoline did not react with acetic anhydride under the same conditions. The structure of the product was determined to be 2-acetyl-1, 2-dihydroisoquinoline-1-acetic acid (V) by means of chemical reactions. Active methylene (or methyl) compounds were observed to react with IV competitively to give the corresponding 1, 2-dihydroisoquinolines when they were heated with IV in acetic anhydride.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have