Abstract

Ethyl 5-pyrimidineacrylates, 5-pyrimidineacrylonitriles, and 5-styrylpyrimidines with alkyl groups at the 2-and 4-positions were synthesized by means of the coupling reaction of 5-halopyrimidines with olefines in the presence of palladium phosphine complex. According to a similar manner, pyridines, quinolines, and isoquinolines with the same substituents at the β-positions were obtained in good yield.

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