Abstract
ABSTRACT Gonadotrophic activity was estimated in individual plasma samples of 46 male and female subjects of all ages. The plasma was extracted by means of an ammonium acetate-ethanol procedure and tested biologically by the mouse uterine weight assay. The values in postmenopausal plasma ranged from 10 to 46 milligram-equivalents of the 2nd International Reference Preparation for Human Menopausal Gonadotrophin per litre. Plasma of men and women in the reproductive years contained 0.6–3.0 and 0.5–2.4 milligram-equivalents of the 2nd IRP per litre. The results in female plasma were assembled according to the day of the menstrual cycle. Though there was no significant difference in the mean values between group A (days 1–9), B (days 10–19) and C (days 20–30), the highest value was observed on the 13th day of the cycle of a 37 years old woman.
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