Abstract
The phagocytosis of starch granules by rabbit peritoneal exudate polymorphonuclear leukocytes measured by the uptake of 131I-labeled human serum albumin was found to be suppressed by anaerobiosis, iodoacetate, malonate, cyanide and ATPase inhibitors. The suppressive effect of iodoacetate can be partially relieved by pyruvate. The results suggest that the tricarboxylic acid cycle and the cytochrome system play important roles in supplying energy for the phagocytic process.
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