Abstract
According to our own procedures of virus isolation and serology, 53 cases of parainfluenza virus infections were found out of 479 infants and children with respiratory illness between September 1963 and December 1965 in Sendai. Virus isolation was positive in 134 cases out of 479 tested, including 60 respiratory syncytial (RS) virus, 28 parainfluenza virus and others. In serological study, poor antibody production in type 2 parainfluenza virus infection was noticed as compared with type 1 or type 3 infections. Three cases from which no viral agent was recovered, showed significant antibody rise against Sendai virus without antibody rise against any other parainfluenza and mumps viruses. In addition, Sendai virus antibody was most frequently found as a heterotypic antibody in these parainfluenza virus infections. Type 1 and type 3 parainfluenza virus infections were observed in spring, whereas type 2 virus infections were observed in autumn and winter. In this epidemiologic and clinical study, it is most notable that the incidence of laryngotracheobronchitis (croup) is less than that in the reports from other European and American countries.
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