Abstract
Methyl 2,3-di-(O-(L-phenylalanyl)-±-D-glucopyranoside and other O-aminoacyl sugars composed of neutral amino acids were synthesized to discover their tastes. Among them, phenylalanine derivatives were strongly bitter [the bitterness of methyl 2,3-di-O-(L-phenylalanyl-L-phenylalanyl-L-phenylalanyl)-±-D-glucopyranoside are equal to that of strychnine], on the other hand, O-aminoacyl sugars composed of amino acids having short side chain were very sweet; The sweetness of methyl 2,3-di-O-(L-±-aminobutyryl)-±-D-glucopyranoside is more than 50 times as strong as that of sucrose.
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