Abstract

Various 2‐phenyloxy‐4,6‐bisarylhydrazino‐1,3,5‐triazines(3a‐f) were prepared by reaction of 2‐ phenyloxy ‐4,6‐dichloro ‐1,3,5‐triazine and various aryl hydrazine derivatives. All the 3a‐f derivatives were characterized by elemental analysis and IR spectral studies. All the compounds were screened for microbial activity against gram‐positive and gram‐negative bacteria.

Highlights

  • Number of derivatives containing s-triazine ring have been reported as hetrocyclic compounds 1

  • Cyanuric chloride and all the aryl hydrazine derivatives(substitution shown in Scheme-1 were obtained as Analar grade from local dealer.2- phenyloxy –4,6-dichloro –1,3,5-triazine was prepared by reported method 4

  • The antibacterial activity of 3a-f compounds was measured on each of these microorganism strains on a potato dextrose agar medium (PDA)

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Summary

Introduction

Number of derivatives containing s-triazine ring have been reported as hetrocyclic compounds 1. The aryl hydrazine derivatives containing s-triazine ring are not reported so far except one instance 4. Cyanuric chloride and all the aryl hydrazine derivatives(substitution shown in Scheme-1 were obtained as Analar grade from local dealer.2- phenyloxy –4,6-dichloro –1,3,5-triazine was prepared by reported method 4. Following general procedure is adopted.The antimicrobial activity of all the compounds was studies at 1000 ppm concentration in vitro. The antibacterial activity of 3a-f compounds was measured on each of these microorganism strains on a potato dextrose agar medium (PDA). After autoclaving the compounds to be tested were inoculated (1000 ppm) in PDA medium at 42oC temperature and mix it than these media were poured in to sterile empty glass petriplates. The antimicrobial activity of all the 3a-f compounds are furnished in Table-2

Results and Discussion
Ar yl -O -Ar yl
Conclusion

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