Abstract
The response of mature spermatozoa to the X-ray induction (500 R and 3000 R) of sex-linked recessive lethals was studied in Drosophila melanogaster males known to be deficient in excision- or post-replication repair of UV damage in somatic cells. The results show that the induced frequencies of recessive lethals in the excision-repair-deficient males ( mei-9 a and mei-9 L1) are similar to those in the appropriate repair-proficient males ( mei + and Berlin-K). However, in the post-replication-repair-deficient males ( w mus(1)101 D1), these frequencies are significantly lower than in the comparable repair-proficient males ( w) after 500 R, but not after 3000 R.
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More From: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
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