Studies on mechanism of entry of EB virus into non-B lymphocytes. Establishment of an EB virus-producing human-tupaia hybrid cell line TuH18.

Abstract

With the use of the EB virus-producing lymphoblastoid cell line H18, an attempt was made to infect the monolayer cell culture of nasopharyngeal tissue from the normal tupaia, and an EB virus-producing, human-tupaia hybrid cell line was established. The mechanism of entry of EB virus into cells other than B lymphocytes is discussed in this paper.