Abstract
Herbal medicines are being used for the treatment of different diseases for centuries. Sustainable development of herbal medicines need the study of their safety, efficacy and standardization are essential. Two commercially available herbal medicines i.e., Ziabetes (dolabi) and Jambadayrist, and a folkloric medicine prepared from four plant materials by a local practitioners were investigated for their chemical compositions. Four compounds were isolated from the extracts of these medicines by silica gel column chromatography. Oleic acid and p-hydroxycinnamic acid were isolated from the aqueous 80%ethanol extract of the folkloric medicine whereas benzoic acid was found to be present in Ziabetes and Jambadayrist. The present investigation revealed that excessive amount of benzoic acid (or sodium benzoate) is being added as preservative in commercial herbal medicines.
Highlights
Use of medicinal plants for treatment of different ailments is as old as human civilization
The objective of the present work is to determine chemical compositions of two commercially available herbal antidiabetic medicines i.e., Ziabetes and Jambadayrist and a folkloric medicine prepared by a local practitioner who treats his patients for diabetes in Jessore area
Ziabetes and Jambadayrist, two commercial antidiabetic herbal medicines were purchased from the herbal medicinal shop of Dhaka city
Summary
Use of medicinal plants for treatment of different ailments is as old as human civilization. Australia and Asia are the three continents where traditional medicine became popular and ~80% of the people in the developing countries are still dependent on plant based medicines (TDR 2005; Newman et al, 2000). The medicines are termed as herbal medicines which are prepared either from aerial parts of herbs or the whole plant or parts of plants i.e., barks, leaves, roots, stems, flowers, fruits and seeds. Herbal products may contain a single herb or combination of several different herbs (Mosihuzzaman and Choudhary, 2008). Raw herbs are available in the market and the formulated products of the herbs are prepared following different pharmacopeia (Mosihuzzaman and Choudhary, 2008)
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