Abstract
43 samples of endometrium from IUD-users with excessive uterine bleeding (MBL>80 ml), normal menstrual blood loss (MBL 0.05). The results also indicated a positive correlation between the amount of MBL and 6-keto-PGF1α concentration in endometrium of IUD-users (r = 0.439;P<0.05). The measurements of both tissue plasminogen. activator (t-PA) and 6-keto-PGI1α concentrations from samples of 28 cases showed a weak positive correlation between t-PA and 6-keto-PGF1α (r = 0.459;P<0.05). Further study is necessary to evaluate the significance of this result. In summary, our studies prove that the increased 6-keto-PGF1α is an important factor contributing to excessive uterine bleeding in IUD-users.
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Schedule a callMore From: Journal of Tongji Medical University = Tong ji yi ke da xue xue bao
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