Abstract
Net glucose production has been studied in liver and kidney cortex slices from normal fasted rats. Only a small amount of net glucose synthesis was observed with individual substrates such as lactate, glycerol, phosphoenol pyruvate, succinate, alanine, aspartate and glutamate. With fructose, an increase in glucose synthesis was observed with an increase in concentration, but similar results were not obtained with lactate. Further studies with combinations of substrates indicate that net glucose synthesis occurs in the following decreasing order: glutamate, glycerol and pyruvate; glutamate and pyruvate; glutamate, glycerol and lactate. Glucose formation by kidney slices was slightly less than that observed in liver. Both tissues gave a similar response to the various substrates tested.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
