Studies on fungal products. Part 17. Isolation and structures of novel indoloditerpenes, emindoles DA and DB, from Emericella desertorum: X-ray molecular structure of emindole DA acetate

Abstract

Together with tremorgenic mycotoxin, paxilline (3), and bicoumarins, desertorins A, B, and C, two new compounds designated emindoles DA (1), C28H39NO, and DB(2), C28H39NO2, have been isolated from the mycelium of Emericella desertorum. The structures of emindoles DA (1) and DB (2) have been determined on the basis of the spectroscopic and chemical investigations of these compounds and an X-ray crystallographic study of emindole DA acetate (4). Emindoles DA (1) and DB (2) are novel Indoloditerpenes biogenetically related to paxilline (3).