STUDIES ON EXPERIMENTAL TYPHOID : THE DISTRIBUTION OF MICROORGANISMS IN THE COURSE OF INFECTION WITH S.ENTERITIDS AND THEIR PATHOIOGICAI STUDIES OF INFECTED MICE ORGANS

Abstract

In the course of infection of mice with S.enteritidis, the distribution of microorganisms in the mice organs were studied. When the mice were infected with 10-7 and 10-5mg of virulent strain 116-54, the number of infected bacteria in the blood and liver was determined by stamp method.The results were shown in Fig. 2 and 3. 24 or 48 hours after the infection the number of bacteria in blood and liver decreased. But 3 days after the infection bacteria increased.The number of bacteria was also determined by plate counting method. As shown in Fig.4 and 5, the number of bacteria in the liver and blood decreased and reached minimum 6 hours after the infection. From this time the number of bacteria increased.The number of bacteria in 1 g of liver was always 100 times that in 1 ml of blood in the course of the infection.The histopathological studies of mice organs were described. The results were shown in figures.