Abstract
The author attempted to produce the arteriosclerosis in various organs in albino rats. Cholesterol, methyl-thiouracil or butter were additionally administered in the albino rats previously loaded with the ATP-ase fraction of the house-rat's kidney and DCA. Besides the vascular lesions in renal arteries as shown in the previous paper, arteriosclerotic changes were produced in the coronary, mesenteric or cerebral arteries, and, in some animals, myocardial fibrosis or cerebral demyelinating lesion were observed. Myocardium ATP-ase fraction was administered in normotensive albino rats, in combination with the loading of cholesterol, methyl-thiouracil or butter. Coronary sclerosis was produced in normotensive albino rats, but no marked vascular lesions were observed in kidney or other organs.
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