Abstract

The glycosaminoglycan content of corneal stroma during transient edema produced by removal of the endothelium was measured. It was observed that this process is associated with a considerable loss of polysaccharides. Both the keratan sulfate and the chondroitin 4-sulfate content were decreased to approximately 50% of their normal values. After healing the tissue assumed a normal appearance and the polysaccharide content returned to its original level. During this process no qualitative changes in the glycosaminoglycan pattern were observed, nor did any other polysaccharide species appear.

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