Abstract

Two new alkaloids, syneilesine and acetylsyneilesine, together with senecionine have been isolated from the roots and aerial parts of Syneilesis palmate MAXIM. (Compositae). The structures of syneilesine and acetylsyneilesine were shown to be (12R), (13R), (14R)-15-ethyl-12, 14-dihydroxy-4, 12, 13-trimethyl-8-oxo-4, 8-secosenec-1-enine and (12R), (13R), (14R)-14-acetoxy-15-ethyl-12-hydroxy-4, 12, 13-trimethyl-8-oxo-4, 8-secosenec-1-enine, respectively.

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