Abstract
Nitrated polycyclic aromatic hydrocarbons (nitrated PAHs) have been detected in various environmental samples and shown to be responsible for a substantial portion of the observed direct-acting mutagenicity in the Salmonella assay by many researchers. This paper describes the results on the comparative decomposition rate of some nitrated PAHs by rat liver homogenate and the micronucleus test in mice after administering 1-nitropyrene, 2-nitrofluorene and 1-aminopyrene.
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