Abstract
Freshly isolated chicken peripheral blood monocytes were used. They were found to be heterogeneous in morphology, but have chemotactic and phagocytic activities, and are capable of respiratory burst. These cells posses a genetic sequecee that can be amplified by a pair of MIP 1-beta primers, indicating that they contain MIP 1-beta chemokine. The RNA from monocytes infected with Newcastle disease virus (NDV) were reverse transcribed, and the transcribed cDNA contains a sequence which can be amplified by a pair of NDV primers, indicating that these cells can support the growth of NDV. NDV infection of monocytes does not alter the existence of MIP-1beta. This finding raises the possibility that monocytes can serve as reservoirs for NDV infection.
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