Abstract
The synthesis of a novel class of antifungal agents, the 3-(2-furanyl)-3-(1 H-imidazol-1-ylmethyl)-2-methyl-5-phenyl(or phenyloxymethyl)isoxazolidines (10–15) is described. When tested in vitro, derivatives 10–15 exerted a potent antifungal activity against dermatophytes, but were less effective against fungi causing systemic infections. However, analogues 10 and 12 showed minimum inhibitory concentration (MIC) values of 2.0 μg/ml against Aspergillus fumigatus.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
