Abstract
The aim of this study was to evaluate the efficacy of Allium sativum in Swiss albino mice against DLA induced. Experimental animals were fed with A. sativum extract, orally for 7 alternative day's. Results shown that A. sativum treated to inhibit the Tumor Necrosis factor alpha (TNF-α) expression due to the presence of sulfur compounds. Concurrently A. sativum extract significantly increases the hemoglobin level and decrease the serum glutamic oxaloacetic transaminase (SGOT) serum glutamate pyruvate transaminase (SGPT) alkaline phosphatase (ALP) and gamma glutamyltransferase levels (γ-GT). The Studies implied that natural compounds have antiinflammatory action.
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