Abstract
Spectrophotometric Determination of acetaminophen in pharmaceutical preparations is described. Acetaminophen was hydrolysed by refluxing with perchloric acid to produce p-aminophenol which was reacted with p-dimethyl aminocinnamaldehyde in dilute trichloracetic acid solution to give a red color, which showed absorption maximum at 520 nm. Interference by the presence of phenacetin and sulpyrine can be eliminated by their extraction with chloroform in basic medium or extraction with ethyl acetate in acidic medium.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
