Studies on 1,3-benzoxazines. II. New rearrangement modes in the reaction of 4-chloro-2,2-dimethyl-2H-1,3-benzoxazine with substituted pyridine N-oxides.

Abstract

New rearrangement modes in the reaction of 4-chloro-2, 2-dimethyl-2H-1, 3-benzoxazine (1) with various α- and/or γ-substituted pyridine N-oxides are described. The benzoxazine moiety was introduced into the side chain and/or β-position of the pyridine ring, in addition to the α-position. possible mechanism of the reactions are discussed.